منابع مشابه
Myotrophin in human heart failure.
OBJECTIVES The goal of this study was to investigate plasma levels of myotrophin in heart failure (HF) and their relationship to gender and disease severity. BACKGROUND Myotrophin is a myocardial hypertrophy-inducing factor initially demonstrated in hypertrophied and cardiomyopathic hearts. Recent evidence suggests an interaction with the transcription factor nuclear factor kappa B (NFkappaB)...
متن کاملcardiomyopathic hamster (UM-X7.1) heart
Objective: Phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P ) is not only a precursor to inositol 1,4,5-trisphosphate (Ins 1,4,5-P ) 2 3 and sn-1,2 diacylglycerol, but also essential for the function of several membrane proteins. The aim of this study was to evaluate the changes in the level of this phospholipid in the cell plasma membrane (sarcolemma, SL) of cardiomyopathic hamster (CMPH) h...
متن کاملHeart cell transplantation improves heart function in dilated cardiomyopathic hamsters.
BACKGROUND Little is known about the effect of heart cell transplantation into the dilated cardiomyopathic myocardium. This study was designed to evaluate the effect of heart cell transplantation into dilated cardiomyopathic hamsters. METHODS AND RESULTS Ventricular heart cells were isolated from 4-week-old BIO 53. 58 hamsters and cultured for 2 weeks before transplantation. The cells were la...
متن کاملRegional in vivo and in vitro characterization of autonomic innervation in cardiomyopathic human heart.
BACKGROUND In contrast to healthy volunteers, regional differences of cardiac autonomic innervation have been described through the use of C11-hydroxyephedrine positron emission tomography (HED-PET) in the left ventricles of patients with dilated cardiomyopathy. The goal of the present study was to correlate HED-PET images with biochemical analysis of tissue samples. METHODS AND RESULTS To as...
متن کاملIncreased oxidative stress in dilated cardiomyopathic heart failure.
In the present study, we assessed oxidative stress in patients with dilated cardiomyopathy of ischemic or idiopathic etiology. For this reason we measured whole blood reduced glutathione, erythrocyte superoxide dismutase, susceptibility of erythrocyte membranes and erythrocytes to peroxidation, and SH content of erythrocyte membranes in 12 patients (8 men and 4 women, ages 31 to 66 years) with ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1993
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.73.1.98